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KMID : 0360220230640060466
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Journal of the Korean Ophthalmological Society
2023 Volume.64 No. 6 p.466 ~ p.472
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Comparison between Placement of an Amniotic Membrane Contact Lens and Temporary Amniotic Membrane Transplantation
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Choi Soo-Young
Choi Jae-Won
Park Woo-Chan
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Abstract
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Purpose: We compared the clinical utilities of an amniotic contact lens and temporary amniotic membrane transplantation in patients with persistent corneal epithelial defects.
Methods: Patients diagnosed with persistent corneal epithelial defects from November 2019 to July 2022 were randomly assigned to either lens placement for 2 weeks or temporary transplantation for 1 week, and the outcomes were retrospectively analyzed. The best-corrected visual acuity, corneal sensation, tear film break-up time, and corneal opacity were measured before and after the interventions. The treatment success rates, recurrences, and other complications were analyzed during the follow- up period.
Results: We placed lenses in 32 patients (32 eyes) and 20 patients (20 eyes) underwent transplantation. In both groups, significant differences in best-corrected visual acuity, corneal sensation, tear film break-up time, and corneal opacity were apparent after intervention vs. before. None of the parameters showed any significant differences in terms of their rates of change.
Conclusions: In patients with persistent corneal epithelial defects, amniotic contact lens placement is an effective outpatient procedure and is not inferior to temporary amniotic membrane transplantation.
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KEYWORD
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Amniotic membrane contact lens, Persistent corneal epithelial defect, Temporary amniotic membrane transplantation
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